BMP10 antibody (AA 317-424) (HRP)

Catalog No. ABIN7145682

The Rabbit Polyclonal anti-BMP10 antibody has been validated for ELISA. It is suitable to detect BMP10 in samples from Human.

Quick Overview for BMP10 antibody (AA 317-424) (HRP) (ABIN7145682)

Target: BMP10 (Bone Morphogenetic Protein 10 (BMP10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMP10 antibody is conjugated to HRP

Application: ELISA

Product Details anti-BMP10 Antibody (HRP)

Binding Specificity: AA 317-424

Purpose: BMP10 Antibody, HRP conjugated

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human Bone morphogenetic protein 10 protein (317-424AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for BMP10

Target: BMP10 (Bone Morphogenetic Protein 10 (BMP10))

Alternative Name: BMP10

Background:

Background: Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.

Aliases: BMP-10 antibody, Bmp10 antibody, BMP10_HUMAN antibody, Bone morphogenetic protein 10 antibody, Bone morphogenetic protein 10 preproprotein antibody, MGC126783 antibody, OTTHUMP00000159973 antibody

UniProt: O95393

Pathways: Hormone Activity, Regulation of Muscle Cell Differentiation