C2CD3 antibody (AA 2079-2265)

Catalog No. ABIN7146159

Product Details anti-C2CD3 Antibody

Target: C2CD3 (C2 Calcium-Dependent Domain Containing 3 (C2CD3))

Binding Specificity: AA 2079-2265

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C2CD3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human C2 domain-containing protein 3 protein (2079-2265AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for C2CD3

Target: C2CD3 (C2 Calcium-Dependent Domain Containing 3 (C2CD3))

Alternative Name: C2CD3 (C2CD3 Products)

Synonyms: AU020772 antibody, RGD1307366 antibody, C2 calcium dependent domain containing 3 antibody, C2 calcium-dependent domain containing 3 antibody, C2CD3 antibody, C2cd3 antibody

Background:

Background: Component of the centrioles that acts as a positive regulator of centriole elongation (PubMed:24997988). Promotes assembly of centriolar distal appendage, a structure at the distal end of the mother centriole that acts as an anchor of the cilium, and is required for recruitment of centriolar distal appendages proteins CEP83, SCLT1, CEP89, FBF1 and CEP164. Not required for centriolar satellite integrity or RAB8 activation. Required for primary cilium formation (PubMed:23769972). Required for sonic hedgehog/SHH signaling and for proteolytic processing of GLI3.

Aliases: C2CD3 antibody, C2 domain-containing protein 3 antibody

UniProt: Q4AC94