CABIN1 antibody (AA 1978-2123) (HRP)
Quick Overview for CABIN1 antibody (AA 1978-2123) (HRP) (ABIN7146277)
Target
See all CABIN1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1978-2123
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Cross-Reactivity
- Human
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Purification
- >95%, Protein G purified
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Immunogen
- Recombinant Human Calcineurin-binding protein cabin-1 protein (1978-2123AA)
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CABIN1 (Calcineurin Binding Protein 1 (CABIN1))
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Alternative Name
- CABIN1
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Background
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Background: May be required for replication-independent chromatin assembly. May serve as a negative regulator of T-cell receptor (TCR) signaling via inhibition of calcineurin. Inhibition of activated calcineurin is dependent on both PKC and calcium signals. Acts as a negative regulator of p53/TP53 by keeping p53 in an inactive state on chromatin at promoters of a subset of it\'s target genes.
Aliases: A330070M20Rik antibody, Cabin 1 antibody, CABIN_HUMAN antibody, Cabin1 antibody, CAIN antibody, Calcineurin binding protein cabin 1 antibody, Calcineurin inhibitor antibody, Calcineurin-binding protein cabin-1 antibody, KIAA0330 antibody, PPP3IN antibody
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UniProt
- Q9Y6J0
Target
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