CCDC109B antibody (Regulatory Subunit) (Biotin)
Quick Overview for CCDC109B antibody (Regulatory Subunit) (Biotin) (ABIN7146319)
Target
See all CCDC109B AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 89-219, Regulatory Subunit
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Purpose
- MCUB Antibody, Biotin conjugated
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Purification
- Antigen Affinity Purified
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Immunogen
- Recombinant Human Calcium uniporter regulatory subunit MCUb, mitochondrial protein (89-219AA)
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Isotype
- IgG
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anti-Coiled-Coil Domain Containing 109B (CCDC109B) (AA 89-219), (Regulatory Subunit) antibody
CCDC109B Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CCDC109B (Coiled-Coil Domain Containing 109B (CCDC109B))
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Alternative Name
- MCUB
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Background
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Background: Negatively regulates the activity of MCU, the mitochondrial inner membrane calcium uniporter, and thereby modulates calcium uptake into the mitochondrion. Does not form functional calcium channels by itself. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
Aliases: MCUB antibody, CCDC109BCalcium uniporter regulatory subunit MCUb antibody, mitochondrial antibody, MCUb antibody, Coiled-coil domain-containing protein 109B antibody
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UniProt
- Q9NWR8
Target
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