ARPP19 antibody (AA 2-105)

Catalog No. ABIN7146624

The Rabbit Polyclonal anti-ARPP19 antibody is suitable to detect ARPP19 in samples from Human. It has been validated for ELISA, IHC and IF.

Quick Overview for ARPP19 antibody (AA 2-105) (ABIN7146624)

Target: ARPP19 (cAMP-Regulated Phosphoprotein, 19kDa (ARPP19))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARPP19 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-ARPP19 Antibody

Binding Specificity: AA 2-105

Purpose: ARPP19 Antibody

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human cAMP-regulated phosphoprotein 19 protein (2-105AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ARPP19

Target: ARPP19 (cAMP-Regulated Phosphoprotein, 19kDa (ARPP19))

Alternative Name: ARPP19

Background:

Background: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase. May indirectly enhance GAP-43 expression.

Aliases: ARP19 antibody, ARP19_HUMAN antibody, ARPP-19 antibody, Arpp19 antibody, cAMP-regulated phosphoprotein 19 antibody

UniProt: P56211

Pathways: Regulation of Carbohydrate Metabolic Process