CHST1 antibody (AA 305-397)

Catalog No. ABIN7146672

The Rabbit Polyclonal anti-CHST1 antibody has been validated for WB, ELISA and IHC. It is suitable to detect CHST1 in samples from Human.

Quick Overview for CHST1 antibody (AA 305-397) (ABIN7146672)

Target: CHST1 (Carbohydrate (Keratan Sulfate Gal-6) Sulfotransferase 1 (CHST1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHST1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-CHST1 Antibody

Binding Specificity: AA 305-397

Cross-Reactivity: Human, Mouse, Rat

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Carbohydrate sulfotransferase 1 protein (305-397AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CHST1

Target: CHST1 (Carbohydrate (Keratan Sulfate Gal-6) Sulfotransferase 1 (CHST1))

Alternative Name: CHST1

Background:

Background: Sulfotransferase that utilizes 3\\\'-phospho-5\\\'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of galactose (Gal) residues of keratan. Has a preference for sulfating keratan sulfate, but it also transfers sulfate to the unsulfated polymer. The sulfotransferase activity on sialyl LacNAc structures is much higher than the corresponding desialylated substrate, and only internal Gal residues are sulfated. May function in the sulfation of sialyl N-acetyllactosamine oligosaccharide chains attached to glycoproteins. Participates in biosynthesis of selectin ligands. Selectin ligands are present in high endothelial cells (HEVs) and play a central role in lymphocyte homing at sites of inflammation.

Aliases: Carbohydrate chondroitin 6 keratan sulfotransferase 1 antibody, Carbohydrate chondroitin 6 keratan sulfotransferase antibody, Carbohydrate keratan sulfate Gal 6 sulfotransferase antibody, Carbohydrate keratan sulfate Gal 6 sulfotransferase 1 antibody, Carbohydrate sulfotransferase 1 antibody, Chst1 antibody, CHST1_HUMAN antibody, EC 2.8.2.21 antibody, Galactose N acetylglucosamine N acetylglucosamine 6 O sulfotransferase 1 antibody, Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 1 antibody, GST 1 antibody, GST-1 antibody, Keratan sulfate Gal 6 sulfotransferase antibody, Keratan sulfate Gal-6 sulfotransferase antibody, KS6ST antibody, KSGal6ST antibody, KSST antibody

UniProt: O43916

Pathways: Glycosaminoglycan Metabolic Process