CPB2 antibody (AA 225-372)

Catalog No. ABIN7146768

The Rabbit Polyclonal anti-CPB2 antibody has been validated for WB, IHC, ELISA and IF. It is suitable to detect CPB2 in samples from Human.

Quick Overview for CPB2 antibody (AA 225-372) (ABIN7146768)

Target: CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPB2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-CPB2 Antibody

Binding Specificity: AA 225-372

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Carboxypeptidase B2 protein (225-372AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CPB2

Target: CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))

Alternative Name: CPB2

Background:

Background: Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down-regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin.

Aliases: CPB2 antibody, Carboxypeptidase B2 antibody, EC 3.4.17.20 antibody, Carboxypeptidase U antibody, CPU antibody, Plasma carboxypeptidase B antibody, pCPB antibody, Thrombin-activable fibrinolysis inhibitor antibody, TAFI antibody

UniProt: Q96IY4

Pathways: Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis