Caspase 1 antibody (AA 220-415)

Catalog No. ABIN7146933

The Rabbit Polyclonal anti-Caspase 1 antibody has been validated for ELISA and IF. It is suitable to detect Caspase 1 in samples from Human.

Quick Overview for Caspase 1 antibody (AA 220-415) (ABIN7146933)

Target: Caspase 1 (CASP1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caspase 1 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Product Details anti-Caspase 1 Antibody

Binding Specificity: AA 220-415

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Caspase-10 protein (220-415AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IF:1:200-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Caspase 1

Target: Caspase 1 (CASP1)

Alternative Name: CASP1

Background:

Background: Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase-3, -4, -6, -7, -8, and -9. Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC.

Aliases: ALPS2 antibody, Apoptotic protease Mch-4 antibody, CASP 10 antibody, CASP-10 antibody, CASP10 antibody, CASPA_HUMAN antibody, Caspase 10 apoptosis related cysteine peptidase antibody, Caspase-10 antibody, Caspase-10 subunit p12 antibody, FADD like ICE2 antibody, Fas associated death domain protein antibody, FAS-associated death domain protein interleukin-1B-converting enzyme 2 antibody, FLICE 2 antibody, FLICE2 antibody, ICE like apoptotic protease 4 antibody, ICE-like apoptotic protease 4 antibody, Interleukin 1B converting enzyme 2 antibody, MCH 4 antibody

UniProt: Q92851

Pathways: Apoptosis, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome