Caspase 10 antibody (AA 220-415) (Biotin)

Catalog No. ABIN7146934

This anti-Caspase 10 antibody is a Rabbit Polyclonal antibody detecting Caspase 10 in ELISA. Suitable for Human.

Quick Overview for Caspase 10 antibody (AA 220-415) (Biotin) (ABIN7146934)

Target: Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caspase 10 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-Caspase 10 Antibody (Biotin)

Binding Specificity: AA 220-415

Purpose: CASP10 Antibody, Biotin conjugated

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human Caspase-10 protein (220-415AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Caspase 10

Target: Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))

Alternative Name: CASP10

Background:

Background: Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase-3, -4, -6, -7, -8, and -9. Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC.

Aliases: ALPS2 antibody, Apoptotic protease Mch-4 antibody, CASP 10 antibody, CASP-10 antibody, CASP10 antibody, CASPA_HUMAN antibody, Caspase 10 apoptosis related cysteine peptidase antibody, Caspase-10 antibody, Caspase-10 subunit p12 antibody, FADD like ICE2 antibody, Fas associated death domain protein antibody, FAS-associated death domain protein interleukin-1B-converting enzyme 2 antibody, FLICE 2 antibody, FLICE2 antibody, ICE like apoptotic protease 4 antibody, ICE-like apoptotic protease 4 antibody, Interleukin 1B converting enzyme 2 antibody, MCH 4 antibody

UniProt: Q92851

Pathways: Apoptosis, Caspase Cascade in Apoptosis