CISD2 antibody (AA 61-135) (FITC)

Catalog No. ABIN7147224

The Rabbit Polyclonal anti-CISD2 antibody has been validated for . It is suitable to detect CISD2 in samples from Human.

Quick Overview for CISD2 antibody (AA 61-135) (FITC) (ABIN7147224)

Target: CISD2 (CDGSH Iron Sulfur Domain 2 (CISD2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CISD2 antibody is conjugated to FITC

Application: Please inquire

Product Details anti-CISD2 Antibody (FITC)

Binding Specificity: AA 61-135

Purpose: CISD2 Antibody, FITC conjugated

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human CDGSH iron-sulfur domain-containing protein 2 protein (61-135AA)

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CISD2

Target: CISD2 (CDGSH Iron Sulfur Domain 2 (CISD2))

Alternative Name: CISD2

Background:

Background: Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator of autophagy.

Aliases: 1500009M05Rik antibody, 1500026J14Rik antibody, 1500031D15Rik antibody, AI848398 antibody, B630006A20Rik antibody, CDGSH iron sulfur domain 2 antibody, CDGSH iron-sulfur domain-containing protein 2 antibody, CDGSH type domain 2 antibody, CISD2 antibody, CISD2_HUMAN antibody, Endoplasmic reticulum intermembrane small protein antibody, ERIS antibody, Miner1 antibody, MitoNEET related 1 antibody, MitoNEET-related 1 protein antibody, NAF-1 antibody, Noxp70 antibody, Nutrient deprivation autophagy factor 1 antibody, Nutrient-deprivation autophagy factor-1 antibody, OTTHUMP00000219576 antibody, RGD1566242 antibody, WFS2 antibody, Zcd2 antibody, Zinc finger antibody, Zinc finger, CDGSH type domain 2 antibody

UniProt: Q8N5K1

Pathways: Activation of Innate immune Response