CISD2 antibody (AA 31-80)

Catalog No. ABIN7227914

The Rabbit Polyclonal anti-CISD2 antibody is suitable to detect CISD2 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for CISD2 antibody (AA 31-80) (ABIN7227914)

Target: CISD2 (CDGSH Iron Sulfur Domain 2 (CISD2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CISD2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CISD2 Antibody

Binding Specificity: AA 31-80

Purpose: Rabbit Anti-CISD2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CISD2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CISD2 protein at AA range: 31-80

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CISD2

Target: CISD2 (CDGSH Iron Sulfur Domain 2 (CISD2))

Alternative Name: CISD2

Background: CDGSH iron-sulfur domain-containing protein 2, Endoplasmic reticulum intermembrane small protein, MitoNEET-related 1 protein, Miner1, Nutrient-deprivation autophagy factor-1, NAF-1The protein encoded by CISD2 is a zinc finger protein that localizes to the endoplasmic reticulum. The encoded protein binds an iron/sulfur cluster and may be involved in calcium homeostasis. Defects in CISD2 are a cause of Wolfram syndrome 2.

Molecular Weight: 14kD

Gene ID: 493856

UniProt: Q8N5K1

Pathways: Activation of Innate immune Response