RAD17 antibody (AA 1-270)

Catalog No. ABIN7147264

Product Details anti-RAD17 Antibody

Target: RAD17

Binding Specificity: AA 1-270

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAD17 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Cell cycle checkpoint protein RAD17 protein (1-270AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RAD17

Target: RAD17

Alternative Name: RAD17 (RAD17 Products)

Synonyms: zgc:91969 antibody, RAD17 antibody, K2A18.21 antibody, K2A18_21 antibody, RADIATION SENSITIVE 17 antibody, CCYC antibody, HRAD17 antibody, R24L antibody, RAD17SP antibody, RAD24 antibody, 9430035O09Rik antibody, MmRad24 antibody, RAD17 checkpoint clamp loader component antibody, Rad17p antibody, RADIATION SENSITIVE 17 antibody, RAD17 antibody, rad17 antibody, ATRAD17 antibody, Rad17 antibody

Background:

Background: Essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. Has a weak ATPase activity required for binding to chromatin. Participates in the recruitment of the RAD1-RAD9-HUS1 complex and RHNO1 onto chromatin, and in CHEK1 activation. May also serve as a sensor of DNA replication progression, and may be involved in homologous recombination.

Aliases: CCYC antibody, Cell cycle checkpoint protein antibody, Cell cycle checkpoint protein RAD17 antibody, FLJ41520 antibody, HRAD 17 antibody, hRad17 antibody, R24L antibody, Rad 17 antibody, Rad 24 antibody, RAD1 (S. pombe) homolog antibody, RAD1 homolog antibody, RAD17 antibody, RAD17 homolog (S. pombe) antibody, RAD17 homolog antibody, Rad17 like protein antibody, RAD17, S. pombe, homolog of antibody, RAD17_HUMAN antibody, RAD17Sp antibody, Rad24 antibody, Rad24, mouse, homolog of antibody, Rad24, S. cerevisiae, homolog of antibody, RF C activator 1 homolog antibody, RF C/activator 1 homolog antibody, RF-C/activator 1 homolog antibody

UniProt: O75943