MEF2D antibody (pSer444) (Cy5)

Catalog No. ABIN710520

Product Details anti-MEF2D Antibody (Cy5)

Target: MEF2D (Myocyte Enhancer Factor 2D (MEF2D))

Binding Specificity: pSer444

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEF2D antibody is conjugated to Cy5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS)

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human MEF2D around the phosphorylation site of Ser444

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MEF2D

Target: MEF2D (Myocyte Enhancer Factor 2D (MEF2D))

Alternative Name: MEF2D (MEF2D Products)

Synonyms: sl1 antibody, sl-1 antibody, XMEF2D antibody, MGC145245 antibody, C80750 antibody, myocyte enhancer factor 2D antibody, MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) antibody, mef2d antibody, MEF2D antibody, Mef2d antibody

Background:

Synonyms: MEF2Dphospho S444, DKFZp686I1536, MADS box transcription factor 2 polypeptide D, Mef2d, MEF2D_HUMAN, myocyte enhancer factor 2D, Myocyte specic enhancer factor 2, polypeptide D, Myocyte specic enhancer factor 2D, myocyte-specic enhancer factor 2D.

Background: MEF2D is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family are involved in control of muscle and neuronal cell differentiation and development, and are regulated by class II histone deacetylases. Fusions of the encoded protein with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) due to a translocation have been found in an acute lymphoblastic leukemia cell line, suggesting a role in leukemogenesis. The encoded protein may also be involved in Parkinson disease and myotonic dystrophy. Alternative splicing results in multiple transcript variants.

Gene ID: 4209