CHD1 antibody (AA 1501-1710)

Catalog No. ABIN7147714

This anti-CHD1 antibody is a Rabbit Polyclonal antibody detecting CHD1 in ELISA, IHC and ChIP. Suitable for Human.

Quick Overview for CHD1 antibody (AA 1501-1710) (ABIN7147714)

Target: CHD1 (Chromodomain Helicase DNA Binding Protein 1 (CHD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHD1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Chromatin Immunoprecipitation (ChIP)

Product Details anti-CHD1 Antibody

Binding Specificity: AA 1501-1710

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Chromodomain-helicase-DNA-binding protein 1 protein (1501-1710AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CHD1

Target: CHD1 (Chromodomain Helicase DNA Binding Protein 1 (CHD1))

Alternative Name: CHD1

Background:

Background: ATP-dependent chromatin-remodeling factor which functions as substrate recognition component of the transcription regulatory histone acetylation (HAT) complex SAGA. Regulates polymerase II transcription. Also required for efficient transcription by RNA polymerase I, and more specifically the polymerase I transcription termination step. Regulates negatively DNA replication. Not only involved in transcription-related chromatin-remodeling, but also required to maintain a specific chromatin configuration across the genome. Is also associated with histone deacetylase (HDAC) activity (By similarity). Required for the bridging of SNF2, the FACT complex, the PAF complex as well as the U2 snRNP complex to H3K4me3. Functions to modulate the efficiency of pre-mRNA splicing in part through physical bridging of spliceosomal components to H3K4me3. Required for maintaining open chromatin and pluripotency in embryonic stem cells.

Aliases: ATP dependent helicase CHD 1 antibody, ATP-dependent helicase CHD1 antibody, CHD 1 antibody, CHD-1 antibody, Chd1 antibody, CHD1_HUMAN antibody, Chromodomain helicase DNA binding protein 1 antibody, Chromodomain-helicase-DNA-binding protein 1 antibody, DKFZp686E2337 antibody, OTTHUMP00000222625 antibody

UniProt: O14646

Pathways: Chromatin Binding