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IRG1 antibody (AA 57-257) (FITC)

IRG1 Reactivity: Human Host: Rabbit Polyclonal FITC
Catalog No. ABIN7147803
$328.90
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  • Target See all IRG1 products
    IRG1 (Immunoresponsive Gene 1 (IRG1))
    Binding Specificity
    • 4
    • 1
    • 1
    AA 57-257
    Reactivity
    • 13
    • 2
    Human
    Host
    • 14
    Rabbit
    Clonality
    • 14
    Polyclonal
    Conjugate
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IRG1 antibody is conjugated to FITC
    Application
    Please inquire
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Cis-aconitate decarboxylase protein (57-257AA)
    Isotype
    IgG
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    IRG1 (Immunoresponsive Gene 1 (IRG1))
    Alternative Name
    ACOD1 (IRG1 Products)
    Synonyms
    CAD antibody, AI323667 antibody, aconitate decarboxylase 1 antibody, ACOD1 antibody, Acod1 antibody
    Background

    Background: Involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells, ACOD1-mediated itaconic acid production contributes to the antimicrobial activity of macrophages. Plays a role in the embryo implantation.

    Aliases: ACOD1 antibody, Aconitate decarboxylase 1 antibody, Aconitate decarboxylase antibody, CAD antibody, Cis aconitate decarboxylase antibody, Immune responsive gene 1 protein homolog antibody, Immune-responsive gene 1 protein homolog antibody, Immunoresponsive 1 homolog (mouse) antibody, Irg1 antibody, IRG1_HUMAN antibody, OC116 antibody, OPTB1 antibody, TCTIRC7 antibody

    UniProt
    A6NK06
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