Cullin 5 antibody (AA 1-300)

Catalog No. ABIN7148758

Product Details anti-Cullin 5 Antibody

Target: Cullin 5 (CUL5)

Binding Specificity: AA 1-300

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cullin 5 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Cullin-5 protein (1-300AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Cullin 5

Target: Cullin 5 (CUL5)

Alternative Name: CUL5 (CUL5 Products)

Synonyms: cul5 antibody, wu:fd17d09 antibody, wu:fi20h12 antibody, xx:11fd17d09 antibody, zgc:66185 antibody, Xcullin5 antibody, CG1401 antibody, CUL5 antibody, Cul5 antibody, Cullin 5 antibody, Cullin5 antibody, Dmel\\CG1401 antibody, cul-5 antibody, vacm-1 antibody, vacm1 antibody, VACM-1 antibody, VACM1 antibody, 4921514I20Rik antibody, 8430423K24Rik antibody, AI852817 antibody, C030032G03Rik antibody, C330021I08Rik antibody, Cullin-5 antibody, cullin 5a antibody, cullin 5 L homeolog antibody, Cullin 5 antibody, cullin 5 antibody, Cullin-5 antibody, cul5a antibody, cul5.L antibody, Cul5 antibody, CUL5 antibody, cul5 antibody, cul-5 antibody

Background:

Background: Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. May form a cell surface vasopressin receptor.

Aliases: CUL 5 antibody, CUL-5 antibody, CUL5 antibody, CUL5_HUMAN antibody, Cullin 5 antibody, Cullin-5 (vasopressin-activated calcium-mobilizing receptor-1) antibody, Cullin-5 antibody, Cullin5 antibody, VACM 1 antibody, VACM-1 antibody, VACM1 antibody, Vasopressin activated calcium mobilizing receptor 1 antibody, Vasopressin activated calcium mobilizing receptor antibody, Vasopressin-activated calcium-mobilizing receptor 1 antibody, Vasopressin-activated calcium-mobilizing receptor-1 antibody

UniProt: Q93034

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development