ATF3 antibody (AA 1-181)

Catalog No. ABIN7148789

This Rabbit Polyclonal antibody specifically detects ATF3 in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for ATF3 antibody (AA 1-181) (ABIN7148789)

Target: ATF3 (Activating Transcription Factor 3 (ATF3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATF3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-ATF3 Antibody

Binding Specificity: AA 1-181

Purpose: ATF3 Antibody

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human Cyclic AMP-dependent transcription factor ATF-3 protein (1-181AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ATF3

Target: ATF3 (Activating Transcription Factor 3 (ATF3))

Alternative Name: ATF3

Background:

Background: This protein binds the cAMP response element (CRE) (consensus: 5\\\'-GTGACGT[AC][AG]-3\\\'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.

Aliases: Activating transcription factor 3 antibody, ATF3 antibody, ATF3_HUMAN antibody, ATF3deltaZip2 antibody, ATF3deltaZip2c antibody, ATF3deltaZip3 antibody, cAMP dependent transcription factor ATF3 antibody, cAMP-dependent transcription factor ATF-3 antibody, Cyclic AMP dependent transcription factor ATF3 antibody, Cyclic AMP-dependent transcription factor ATF-3 antibody

UniProt: P18847

Pathways: Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response