Cyclin H antibody (AA 261-319) (Biotin)

Catalog No. ABIN7148940

The Rabbit Polyclonal anti-Cyclin H antibody has been validated for ELISA. It is suitable to detect Cyclin H in samples from Human.

Quick Overview for Cyclin H antibody (AA 261-319) (Biotin) (ABIN7148940)

Target: Cyclin H (CCNH)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclin H antibody is conjugated to Biotin

Application: ELISA

Product Details anti-Cyclin H Antibody (Biotin)

Binding Specificity: AA 261-319

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Cyclin-H protein (261-319AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Cyclin H

Target: Cyclin H (CCNH)

Alternative Name: CCNH

Background:

Background: Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.

Aliases: 6330408H09Rik antibody, AI661354 antibody, AV102684 antibody, AW538719 antibody, CAK antibody, CAK complex subunit antibody, ccnh antibody, CCNH_HUMAN antibody, CDK activating kinase antibody, CDK activating kinase complex subunit antibody, Cyclin dependent kinase activating kinase antibody, cyclin dependent kinase activating kinase complex subunit antibody, Cyclin H antibody, Cyclin-H antibody, CyclinH antibody, MO15 associated protein antibody, MO15-associated protein antibody, p34 antibody, p36 antibody, p37 antibody

UniProt: P51946

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases, M Phase