Cyclin Y antibody (AA 2-170)

Catalog No. ABIN7148955

Product Details anti-Cyclin Y Antibody

Target: Cyclin Y (CCNY)

Binding Specificity: AA 2-170

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclin Y antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Cyclin-Y protein (2-170AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000, IF:1:200-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Cyclin Y

Target: Cyclin Y (CCNY)

Alternative Name: CCNY (CCNY Products)

Synonyms: CG14939 antibody, Dcyclin Y antibody, Dmel\\CG14939 antibody, anon-WO0118547.165 antibody, i182 antibody, C10orf9 antibody, CBCP1 antibody, CCNX antibody, CFP1 antibody, 1700025H17Rik antibody, 3110050L10Rik antibody, 4631402G10Rik antibody, 5730405I09Rik antibody, RGD1565969 antibody, cyclin Y antibody, Cyclin Y antibody, cyclin Y like 1 antibody, CCNY antibody, CycY antibody, Ccny antibody, CCNYL1 antibody

Background:

Background: Positive regulatory subunit of the cyclin-dependent kinases CDK14/PFTK1 and CDK16. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma membrane and promoting phosphorylation of LRP6, leading to the activation of the Wnt signaling pathway. Recruits CDK16 to the plasma membrane. Isoform 3 might play a role in the activation of MYC-mediated transcription.

Aliases: CCNY antibody, C10orf9 antibody, CBCP1 antibody, CFP1Cyclin-Y antibody, Cyc-Y antibody, Cyclin box protein 1 antibody, Cyclin fold protein 1 antibody, cyclin-X antibody

UniProt: Q8ND76