Cyclin Y antibody (AA 2-170) (FITC)
Quick Overview for Cyclin Y antibody (AA 2-170) (FITC) (ABIN7148957)
Target
See all Cyclin Y (CCNY) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 2-170
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Cross-Reactivity
- Human
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Purification
- >95%, Protein G purified
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Immunogen
- Recombinant Human Cyclin-Y protein (2-170AA)
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Isotype
- IgG
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Cyclin Y (CCNY)
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Alternative Name
- CCNY
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Background
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Background: Positive regulatory subunit of the cyclin-dependent kinases CDK14/PFTK1 and CDK16. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma membrane and promoting phosphorylation of LRP6, leading to the activation of the Wnt signaling pathway. Recruits CDK16 to the plasma membrane. Isoform 3 might play a role in the activation of MYC-mediated transcription.
Aliases: CCNY antibody, C10orf9 antibody, CBCP1 antibody, CFP1Cyclin-Y antibody, Cyc-Y antibody, Cyclin box protein 1 antibody, Cyclin fold protein 1 antibody, cyclin-X antibody
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UniProt
- Q8ND76
Target
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