CBS antibody (AA 1-413) (Biotin)

Catalog No. ABIN7148966

This Rabbit Polyclonal antibody specifically detects CBS in ELISA. It exhibits reactivity toward Human.

Quick Overview for CBS antibody (AA 1-413) (Biotin) (ABIN7148966)

Target: CBS (Cystathionine-beta-Synthase (CBS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBS antibody is conjugated to Biotin

Application: ELISA

Product Details anti-CBS Antibody (Biotin)

Binding Specificity: AA 1-413

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Cystathionine beta-synthase protein (1-413AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CBS

Target: CBS (Cystathionine-beta-Synthase (CBS))

Alternative Name: CBS

Background:

Background: Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine (PubMed:23981774, PubMed:20506325, PubMed:23974653). Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons (By similarity).

Aliases: AI047524 antibody, AI303044 antibody, Beta thionase antibody, Beta-thionase antibody, Cbs antibody, Cbs cystathionine beta-synthase antibody, CBS_HUMAN antibody, Cystathionine beta synthase antibody, Cystathionine beta-synthase antibody, EC 4.2.1.22 antibody, HIP 4 antibody, HIP4 antibody, Methylcysteine synthase antibody, MGC18856 antibody, MGC18895 antibody, MGC37300 antibody, OTTHUMP00000109416 antibody, OTTHUMP00000109418 antibody, Serine sulfhydrase antibody

UniProt: P35520