ATG4D antibody (AA 14-43)

Catalog No. ABIN7149030

The Rabbit Polyclonal anti-ATG4D antibody has been validated for WB, ELISA, IHC and IF. It is suitable to detect ATG4D in samples from Human.

Quick Overview for ATG4D antibody (AA 14-43) (ABIN7149030)

Target: ATG4D (Autophagy related 4D Cysteine Peptidase (ATG4D))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATG4D antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-ATG4D Antibody

Binding Specificity: AA 14-43

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Cysteine protease ATG4D protein (14-43AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000, IF:1:200-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ATG4D

Target: ATG4D (Autophagy related 4D Cysteine Peptidase (ATG4D))

Alternative Name: ATG4D

Background:

Background: Cysteine protease ATG4D: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.

Aliases: 9830134P12Rik antibody, APG4 autophagy 4 homolog D antibody, APG4 D antibody, APG4, S. cerevisiae, homolog of, D antibody, APG4D antibody, ATG4 autophagy related 4 homolog D (S. cerevisiae) antibody, Atg4d antibody, ATG4D_HUMAN antibody, Atg4dl antibody, AUT like 4 cysteine endopeptidase antibody, AUT-like 4 cysteine endopeptidase antibody, AUTL4 antibody, Autophagin 4 antibody, Autophagin-4 antibody, autophagy 4, S. cerevisiae, homolog of, D antibody, autophagy related 4D, cysteine peptidase antibody, Autophagy related cysteine endopeptidase 4 antibody, Autophagy related protein 4 homolog D antibody, Autophagy-related cysteine endopeptidase 4 antibody, Autophagy-related protein 4 homolog D antibody, Cysteine protease ATG4D antibody, Cysteine protease involved in autophagy antibody, MGC31226 antibody

UniProt: Q86TL0

Pathways: Autophagy