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CYFIP1 antibody (AA 320-449)

CYFIP1 Reactivity: Human ELISA, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7149328
  • Target See all CYFIP1 Antibodies
    CYFIP1 (Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1))
    Binding Specificity
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 320-449
    Reactivity
    • 19
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 20
    • 1
    Rabbit
    Clonality
    • 21
    Polyclonal
    Conjugate
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CYFIP1 antibody is un-conjugated
    Application
    • 10
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunofluorescence (IF)
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Cytoplasmic FMR1-interacting protein 1 protein (320-449AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    CYFIP1 (Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1))
    Alternative Name
    CYFIP1 (CYFIP1 Products)
    Synonyms
    TUBGCP5 antibody, P140SRA-1 antibody, SHYC antibody, SRA1 antibody, E030028J09Rik antibody, P140sra1 antibody, Shyc antibody, Sra-1 antibody, Sra1 antibody, l(7)1Rl antibody, l71Rl antibody, l7Rl1 antibody, mKIAA0068 antibody, pl-1 antibody, CY antibody, CYFIP antibody, fb15a06 antibody, wu:fb15a06 antibody, cytoplasmic FMR1 interacting protein 1 antibody, CYFIP1 antibody, cyfip1 antibody, Cyfip1 antibody
    Background

    Background: Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA (By similarity). Regulates formation of membrane ruffles and lamellipodia. Plays a role in axon outgrowth. Binds to F-actin but not to RNA. Part of the WAVE complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. Regulator of epithelial morphogenesis. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity). May act as an invasion suppressor in cancers.

    Aliases: CY antibody, CYFIP 1 antibody, CYFIP1 antibody, CYFP1_HUMAN antibody, Cytoplasmic FMR1 interacting protein 1 antibody, Cytoplasmic FMR1-interacting protein 1 antibody, FLJ45151 antibody, KIAA0068 antibody, p140sra 1 antibody, p140sra-1 antibody, P140SRA1 antibody, Selective hybridizing clone antibody, SHYC antibody, Specifically Rac1 associated protein 1 antibody, Specifically Rac1-associated protein 1 antibody, SRA 1 antibody, Sra-1 antibody, SRA1 antibody

    UniProt
    Q7L576
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