CYFIP1 antibody (AA 320-449) (HRP)

Catalog No. ABIN7149331

This anti-CYFIP1 antibody is a Rabbit Polyclonal antibody detecting CYFIP1 in ELISA. Suitable for Human.

Quick Overview for CYFIP1 antibody (AA 320-449) (HRP) (ABIN7149331)

Target: CYFIP1 (Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYFIP1 antibody is conjugated to HRP

Application: ELISA

Product Details anti-CYFIP1 Antibody (HRP)

Binding Specificity: AA 320-449

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Cytoplasmic FMR1-interacting protein 1 protein (320-449AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CYFIP1

Target: CYFIP1 (Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1))

Alternative Name: CYFIP1

Background:

Background: Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA (By similarity). Regulates formation of membrane ruffles and lamellipodia. Plays a role in axon outgrowth. Binds to F-actin but not to RNA. Part of the WAVE complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. Regulator of epithelial morphogenesis. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity). May act as an invasion suppressor in cancers.

Aliases: CY antibody, CYFIP 1 antibody, CYFIP1 antibody, CYFP1_HUMAN antibody, Cytoplasmic FMR1 interacting protein 1 antibody, Cytoplasmic FMR1-interacting protein 1 antibody, FLJ45151 antibody, KIAA0068 antibody, p140sra 1 antibody, p140sra-1 antibody, P140SRA1 antibody, Selective hybridizing clone antibody, SHYC antibody, Specifically Rac1 associated protein 1 antibody, Specifically Rac1-associated protein 1 antibody, SRA 1 antibody, Sra-1 antibody, SRA1 antibody

UniProt: Q7L576