DIS3L antibody (AA 1-300)

Catalog No. ABIN7150013

Product Details anti-DIS3L Antibody

Target: DIS3L (DIS3-Like Exonuclease 1 (DIS3L))

Binding Specificity: AA 1-300

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DIS3L antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human DIS3-like exonuclease 1 protein (1-300AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for DIS3L

Target: DIS3L (DIS3-Like Exonuclease 1 (DIS3L))

Alternative Name: DIS3L (DIS3L Products)

Synonyms: DIS3L1 antibody, AV340375 antibody, RGD1308959 antibody, zgc:158615 antibody, DIS3 like exosome 3'-5' exoribonuclease antibody, DIS3-like exosome 3'-5' exoribonuclease antibody, DIS3L antibody, dis3l antibody, Dis3l antibody, dis3l.L antibody

Background:

Background: Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3\\\'->5\\\' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3\\\' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA.

Aliases: DIS3L antibody, DIS3L1 antibody, KIAA1955DIS3-like exonuclease 1 antibody, EC 3.1.13.- antibody

UniProt: Q8TF46