LIG3 antibody (AA 809-928) (Biotin)

Catalog No. ABIN7150194

The Rabbit Polyclonal anti-LIG3 antibody has been validated for ELISA. It is suitable to detect LIG3 in samples from Human.

Quick Overview for LIG3 antibody (AA 809-928) (Biotin) (ABIN7150194)

Target: LIG3 (Ligase III, DNA, ATP-Dependent (LIG3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LIG3 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-LIG3 Antibody (Biotin)

Binding Specificity: AA 809-928

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human DNA ligase 3 protein (809-928AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for LIG3

Target: LIG3 (Ligase III, DNA, ATP-Dependent (LIG3))

Alternative Name: LIG3

Background:

Background: Isoform 3 functions as heterodimer with DNA-repair protein XRCC1 in the nucleus and can correct defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents. Isoform 1 is targeted to mitochondria, where it functions as DNA ligase in mitochondrial base-excision DNA repair (PubMed:10207110, PubMed:24674627).

Aliases: D11Wsu78e antibody, DNA ligase antibody, DNA ligase 3 antibody, DNA ligase III antibody, DNLI3_HUMAN antibody, LIG 3 antibody, LIG2 antibody, LIG3 antibody, Ligase II, DNA, ATP dependent antibody, Ligase III DNA ATP dependent antibody, MGC78176 antibody, OTTMUSP00000000875 antibody, Polydeoxyribonucleotide synthase [ATP] 3 antibody, Polydeoxyribonucleotide synthase [ATP] antibody, Polydeoxyribonucleotide synthase antibody, RP23-316C11.6 antibody

UniProt: P49916

Pathways: DNA Damage Repair