POLK antibody (AA 227-337)

Catalog No. ABIN7150255

This anti-POLK antibody is a Rabbit Polyclonal antibody detecting POLK in WB and ELISA. Suitable for Human.

Quick Overview for POLK antibody (AA 227-337) (ABIN7150255)

Target: POLK (Polymerase (DNA Directed) kappa (POLK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLK antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-POLK Antibody

Binding Specificity: AA 227-337

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human DNA polymerase kappa protein (227-337AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for POLK

Target: POLK (Polymerase (DNA Directed) kappa (POLK))

Alternative Name: POLK

Background:

Background: DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Depending on the context, it inserts the correct base, but causes frequent base transitions, transversions and frameshifts. Lacks 3\\\'-5\\\' proofreading exonuclease activity. Forms a Schiff base with 5\\\'-deoxyribose phosphate at abasic sites, but does not have lyase activity.

Aliases: DinB homolog 1 (E. coli) antibody, DINB protein antibody, DINB1 antibody, DINP antibody, DNA damage inducible protein b antibody, DNA polymerase kappa antibody, Polk antibody, POLK_HUMAN antibody, POLQ antibody, Polymerase (DNA directed) kappa antibody, polymerase, DNA, kappa antibody

UniProt: Q9UBT6

Pathways: DNA Damage Repair