MCM2 antibody (AA 2-904)

Catalog No. ABIN7150328

This Rabbit Polyclonal antibody specifically detects MCM2 in WB, IHC, ELISA and IF. It exhibits reactivity toward Human.

Quick Overview for MCM2 antibody (AA 2-904) (ABIN7150328)

Target: MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCM2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-MCM2 Antibody

Binding Specificity: AA 2-904

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human DNA replication licensing factor MCM2 protein (2-904AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000, IF:1:200-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MCM2

Target: MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))

Alternative Name: MCM2

Background:

Background: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for \\\'once per cell cycle\\\' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division.

Aliases: BM28 antibody, CCNL 1 antibody, CCNL1 antibody, CDC like 1 antibody, cdc19 antibody, CDCL 1 antibody, CDCL1 antibody, Cell devision cycle like 1 antibody, Cyclin like 1 antibody, D3S3194 antibody, DNA replication licensing factor MCM2 antibody, KIAA0030 antibody, MCM 2 antibody, MCM2 antibody, MCM2 minichromosome maintenance deficient 2 mitotin antibody, MCM2 minichromosome maintenance deficient 2 mitotin (S. cerevisiae) antibody, MCM2 minichromosome maintenance deficient 2, mitotin antibody, MCM2_HUMAN antibody, MGC10606 antibody, Minichromosome maintenance complex component 2 antibody, Minichromosome maintenance deficient 2 (mitotin) antibody, Minichromosome maintenance deficient 2 mitotin antibody, Minichromosome maintenance protein 2 antibody, Minichromosome maintenance protein 2 homolog antibody, Mitotin antibody, Nuclear protein BM28 antibody, OTTHUMP00000216047 antibody, OTTHUMP00000216050 antibody

UniProt: P49736

Pathways: DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA