MCM3 antibody (AA 1-295)

Catalog No. ABIN7150332

The Rabbit Polyclonal anti-MCM3 antibody has been validated for WB, IHC, ELISA and ChIP. It is suitable to detect MCM3 in samples from Human.

Quick Overview for MCM3 antibody (AA 1-295) (ABIN7150332)

Target: MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCM3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Chromatin Immunoprecipitation (ChIP)

Product Details anti-MCM3 Antibody

Binding Specificity: AA 1-295

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human DNA replication licensing factor MCM3 protein (1-295AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MCM3

Target: MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))

Alternative Name: MCM3

Background:

Background: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for \\\'once per cell cycle\\\' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for DNA replication and cell proliferation.

Aliases: Cervical cancer proto oncogene 5 antibody, DNA polymerase alpha holoenzyme associated P1 antibody, DNA polymerase alpha holoenzyme associated protein P1 antibody, DNA polymerase alpha holoenzyme-associated protein P1 antibody, DNA replication factor MCM3 antibody, DNA replication licensing factor mcm3 antibody, HCC 5 antibody, HCC5 antibody, hRlf beta subunit antibody, Human cervical cancer proto oncogene 5 antibody, MCM 3 antibody, mcm3 antibody, MCM3 minichromosome maintenance deficient 3 antibody, MCM3_HUMAN antibody, MGC1157 antibody, Minichromosome maintenance complex component 3 antibody, Minichromosome maintenance deficient 3 antibody, Minichromosome maintenance protein 3 antibody, P1 h antibody, P1 MCM3 antibody, P1 Protein antibody, P1-MCM3 antibody, P1.h antibody, p102 antibody, P102 protein antibody, Replication licensing factor beta subunit antibody, RLF beta subunit antibody, RLF subunit beta antibody, RLFB antibody

UniProt: P25205

Pathways: DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA