OPA1 antibody (AA 183-351) (HRP)

Catalog No. ABIN7150844

Product Details anti-OPA1 Antibody (HRP)

Target: OPA1 (Optic Atrophy 1 (Autosomal Dominant) (OPA1))

Binding Specificity: AA 183-351

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OPA1 antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Dynamin-like 120 kDa protein, mitochondrial protein (183-351AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for OPA1

Target: OPA1 (Optic Atrophy 1 (Autosomal Dominant) (OPA1))

Alternative Name: OPA1 (OPA1 Products)

Synonyms: 1200011N24Rik antibody, AI225888 antibody, AI847218 antibody, lilr3 antibody, mKIAA0567 antibody, MGM1 antibody, NPG antibody, NTG antibody, largeG antibody, fk62d06 antibody, wu:fb77a10 antibody, wu:fk62d06 antibody, zgc:92092 antibody, OPA1, mitochondrial dynamin like GTPase antibody, optic atrophy 1 (autosomal dominant) antibody, Opa1 antibody, OPA1 antibody, opa1 antibody

Background:

Background: Dynamin-related GTPase required for mitochondrial fusion and regulation of apoptosis. May form a diffusion barrier for proteins stored in mitochondrial cristae. Proteolytic processing in response to intrinsic apoptotic signals may lead to disassembly of OPA1 oligomers and release of the caspase activator cytochrome C (CYCS) into the mitochondrial intermembrane space. May also play a role in mitochondrial genome maintenance.

Aliases: Dynamin like 120 kDa protein antibody, Dynamin like 120 kDa protein, mitochondrial antibody, Dynamin-like 120 kDa protein, form S1 antibody, FLJ12460 antibody, Juvenile kjer type optic atrophy antibody, KIAA0567 antibody, KJER type antibody, Large GTP binding protein antibody, largeG antibody, MGM1 antibody, Mitochondrial dynamin like 120 kDa protein antibody, Mitochondrial dynamin like GTPase antibody, NPG antibody, NTG antibody, OAK antibody, OPA 1 antibody, opa1 antibody, OPA1 gene antibody, OPA1_HUMAN antibody, Optic atrophy 1 (autosomal dominant) antibody, OPTIC ATROPHY 1 antibody, Optic atrophy 1 gene protein antibody, Optic atrophy 1 homolog (human) antibody, Optic atrophy protein 1 antibody, Optic atrophy protein 1 homolog antibody

UniProt: O60313

Pathways: Tube Formation