LNX1 antibody (AA 133-259) (Biotin)

Catalog No. ABIN7151054

This Rabbit Polyclonal antibody specifically detects LNX1 in ELISA. It exhibits reactivity toward Human.

Quick Overview for LNX1 antibody (AA 133-259) (Biotin) (ABIN7151054)

Target: LNX1 (Ligand of Numb-Protein X 1 (LNX1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LNX1 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-LNX1 Antibody (Biotin)

Binding Specificity: AA 133-259

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human E3 ubiquitin-protein ligase LNX protein (133-259AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for LNX1

Target: LNX1 (Ligand of Numb-Protein X 1 (LNX1))

Alternative Name: LNX1

Background:

Background: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65 (By similarity).

Aliases: LNX1 antibody, LNX antibody, PDZRN2 antibody, UNQ574/PRO1136 antibody, E3 ubiquitin-protein ligase LNX antibody, EC 2.3.2.27 antibody, Ligand of Numb-protein X 1 antibody, Numb-binding protein 1 antibody, PDZ domain-containing RING finger protein 2 antibody, RING-type E3 ubiquitin transferase LNX antibody

UniProt: Q8TBB1