PDZRN3 antibody (AA 133-404)

Catalog No. ABIN7151097

The Rabbit Polyclonal anti-PDZRN3 antibody has been validated for WB, ELISA, IHC and IF. It is suitable to detect PDZRN3 in samples from Human.

Quick Overview for PDZRN3 antibody (AA 133-404) (ABIN7151097)

Target: PDZRN3 (PDZ Domain Containing Ring Finger 3 (PDZRN3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDZRN3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PDZRN3 Antibody

Binding Specificity: AA 133-404

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human E3 ubiquitin-protein ligase PDZRN3 protein (133-404AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:2000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PDZRN3

Target: PDZRN3 (PDZ Domain Containing Ring Finger 3 (PDZRN3))

Alternative Name: PDZRN3

Background:

Background: E3 ubiquitin-protein ligase. Plays an important role in regulating the surface level of MUSK on myotubes. Mediates the ubiquitination of MUSK, promoting its endocytosis and lysosomal degradation. Might contribute to terminal myogenic differentiation (By similarity).

Aliases: E3 ubiquitin-protein ligase PDZRN3 antibody, KIAA1095 antibody, Ligand of Numb protein X 3 antibody, likely ortholog of mouse semaF cytoplasmic domain associated protein 3 antibody, LNX3 antibody, PDZ domain containing ring finger 3 antibody, PDZ domain-containing RING finger protein 3 antibody, Pdzrn3 antibody, Protein SEMACAP3 antibody, PZRN3_HUMAN antibody, SEMACAP3 antibody, Semaphorin cytoplasmic domain associated protein antibody, Semaphorin cytoplasmic domain-associated protein 3 antibody, SEMCAP3 antibody

UniProt: Q9UPQ7

Pathways: Skeletal Muscle Fiber Development