TRIM37 antibody (AA 301-600) (Biotin)

Catalog No. ABIN7151267

This Rabbit Polyclonal antibody specifically detects TRIM37 in ELISA. It exhibits reactivity toward Human.

Quick Overview for TRIM37 antibody (AA 301-600) (Biotin) (ABIN7151267)

Target: TRIM37 (Tripartite Motif Containing 37 (TRIM37))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM37 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-TRIM37 Antibody (Biotin)

Binding Specificity: AA 301-600

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human E3 ubiquitin-protein ligase TRIM37 protein (301-600AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TRIM37

Target: TRIM37 (Tripartite Motif Containing 37 (TRIM37))

Alternative Name: TRIM37

Background:

Background: E3 ubiquitin-protein ligase required to prevent centriole reduplication (PubMed:15885686, PubMed:23769972). Probably acts by ubiquitinating positive regulators of centriole reduplication (PubMed:23769972). Mediates monoubiquitination of \'Lys-119\' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression: associates with some Polycomb group (PcG) multiprotein PRC2-like complex and mediates repression of target genes (PubMed:25470042). Has anti-HIV activity (PubMed:24317724).

Aliases: E3 ubiquitin protein ligase TRIM37 antibody, E3 ubiquitin-protein ligase TRIM37 antibody, KIAA0898 antibody, MUL antibody, MUL protein antibody, Mulibrey nanism gene antibody, Mulibrey nanism protein antibody, POB 1 antibody, POB1 antibody, RING B box coiled coil protein antibody, TEF 3 antibody, TEF3 antibody, TRI37_HUMAN antibody, TRIM 37 antibody, Trim37 antibody, Tripartite motif containing 37 antibody, Tripartite motif containing 37 protein antibody, Tripartite motif containing protein 37 antibody, Tripartite motif-containing protein 37 antibody

UniProt: O94972