ENPP2 antibody (AA 564-863)
Quick Overview for ENPP2 antibody (AA 564-863) (ABIN7151389)
Target
See all ENPP2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- AA 564-863
-
Cross-Reactivity
- Human
-
Purification
- Antigen Affinity Purified
-
Immunogen
- Recombinant Human Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 protein (564-863AA)
-
Isotype
- IgG
-
-
-
-
Application Notes
- Recommended dilution: IHC:1:20-1:200,
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- -20 °C,-80 °C
-
Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- ENPP2 (Ectonucleotide Pyrophosphatase / phosphodiesterase 2 (ENPP2))
-
Alternative Name
- ENPP2
-
Background
-
Background: Hydrolyzes lysophospholipids to produce lysophosphatidic acid (LPA) in extracellular fluids. Major substrate is lysophosphatidylcholine. Also can act on sphingosylphosphphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. Can hydrolyze, in vitro, bis-pNPP, to some extent pNP-TMP, and barely ATP. Involved in several motility-related processes such as angiogenesis and neurite outgrowth. Acts as an angiogenic factor by stimulating migration of smooth muscle cells and microtubule formation. Stimulates migration of melanoma cells, probably via a pertussis toxin-sensitive G protein. May have a role in induction of parturition. Possible involvement in cell proliferation and adipose tissue development. Tumor cell motility-stimulating factor.
Aliases: ATX antibody, ATX X antibody, Autotaxin antibody, Autotaxin t antibody, E NPP 2 antibody, E-NPP 2 antibody, Ectonucleotide pyrophosphatase/phosphodiesterase 2 antibody, Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 antibody, Enpp2 antibody, ENPP2_HUMAN antibody, Extracellular lysophospholipase D antibody, FLJ26803 antibody, LysoPLD antibody, NPP2 antibody, PD IALPHA antibody, PDNP2 antibody, Phosphodiesterase I alpha antibody, Phosphodiesterase I/nucleotide pyrophosphatase 2 antibody, Plasma lysophospholipase D antibody
-
UniProt
- Q13822
Target
-