TPRKB antibody (AA 1-175) (Biotin)

Catalog No. ABIN7151468

Product Details anti-TPRKB Antibody (Biotin)

Target: TPRKB (TP53RK Binding Protein (TPRKB))

Binding Specificity: AA 1-175

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TPRKB antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human EKC/KEOPS complex subunit TPRKB protein (1-175AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TPRKB

Target: TPRKB (TP53RK Binding Protein (TPRKB))

Alternative Name: TPRKB (TPRKB Products)

Synonyms: 0610033G21Rik antibody, 1810034M08Rik antibody, Cgi-121 antibody, DRWMS1 antibody, mDRWMS1 antibody, RGD1309786 antibody, cgi-121 antibody, MGC75657 antibody, TPRKB antibody, zgc:101896 antibody, TP53RK binding protein antibody, Tp53rk binding protein antibody, TP53RK binding protein L homeolog antibody, TPRKB antibody, Tprkb antibody, tprkb antibody, tprkb.L antibody

Background:

Background: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t(6)A activity of the complex. TPRKB is not required for tRNA modification.

Aliases: CGI 121 antibody, My019 antibody, PRPK (p53 related protein kinase) binding protein antibody, PRPK-binding protein antibody, TP53RK binding protein antibody, TP53RK-binding protein antibody, Tprkb antibody, TPRKB_HUMAN antibody

UniProt: Q9Y3C4