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EPH Receptor A5 antibody (AA 246-514) (FITC)

This anti-EPH Receptor A5 antibody is a Rabbit Polyclonal antibody detecting EPH Receptor A5 in . Suitable for Human.
Catalog No. ABIN7151845

Quick Overview for EPH Receptor A5 antibody (AA 246-514) (FITC) (ABIN7151845)

Target

See all EPH Receptor A5 (EPHA5) Antibodies
EPH Receptor A5 (EPHA5)

Reactivity

  • 51
  • 27
  • 11
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
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Human

Host

  • 42
  • 11
Rabbit

Clonality

  • 42
  • 11
Polyclonal

Conjugate

  • 28
  • 5
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This EPH Receptor A5 antibody is conjugated to FITC

Application

Please inquire
  • Binding Specificity

    • 8
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    • 5
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    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    • 1
    AA 246-514

    Cross-Reactivity

    Human

    Purification

    >95%, Protein G purified

    Immunogen

    Recombinant Human Ephrin type-A receptor 5 protein (246-514AA)

    Isotype

    IgG
  • Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C,-80 °C

    Storage Comment

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    EPH Receptor A5 (EPHA5)

    Alternative Name

    EPHA5

    Background

    Background: Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 most probably constitutes the cognate/functional ligand for EPHA5. Functions as an axon guidance molecule during development and may be involved in the development of the retinotectal, entorhino-hippocampal and hippocamposeptal pathways. Together with EFNA5 plays also a role in synaptic plasticity in adult brain through regulation of synaptogenesis. In addition to its function in the nervous system, the interaction of EPHA5 with EFNA5 mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion (By similarity).

    Aliases: Brain-specific kinase antibody, bsk antibody, CEK 7 antibody, Eck like sequence 1 antibody, EHK 1 antibody, EHK-1 antibody, EK7 antibody, Els 1 antibody, EPH homology kinase 1 antibody, EPH-like kinase 7 antibody, EPHA5 antibody, EPHA5_HUMAN antibody, Ephrin type A receptor 5 antibody, Ephrin type-A receptor 5 antibody, HEK 7 antibody, hEK7 antibody, Receptor protein tyrosine kinase HEK 7 antibody, Rek 7 antibody, TYRO 4 antibody, Tyrosine protein kinase receptor EHK 1 antibody

    UniProt

    P54756

    Pathways

    RTK Signaling
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