Ephrin B1 antibody (AA 28-237)

Catalog No. ABIN7151877

The Rabbit Polyclonal anti-Ephrin B1 antibody has been validated for ELISA and IHC. It is suitable to detect Ephrin B1 in samples from Human.

Quick Overview for Ephrin B1 antibody (AA 28-237) (ABIN7151877)

Target: Ephrin B1 (EFNB1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ephrin B1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-Ephrin B1 Antibody

Binding Specificity: AA 28-237

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Ephrin-B1 protein (28-237AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Ephrin B1

Target: Ephrin B1 (EFNB1)

Alternative Name: EFNB1

Background:

Background: Binds to the receptor tyrosine kinases EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons. Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to the receptor tyrosine kinases EPHB3 (preferred), EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons.

Aliases: CFND antibody, CFNS antibody, Craniofrontonasal syndrome (craniofrontonasal dysplasia) antibody, EFL 3 antibody, EFL-3 antibody, EFL3 antibody, EFNB1 antibody, EFNB1_HUMAN antibody, Elk L antibody, ELK ligand antibody, ELK-L antibody, Eph related receptor tyrosine kinase ligand 2 antibody, EPH-related receptor tyrosine kinase ligand 2 antibody, Ephrin-B1 antibody, EPLG2 antibody, LERK 2 antibody, LERK-2 antibody, LERK2 antibody, Ligand of eph related kinase 2 antibody, MGC8782 antibody

UniProt: P98172

Pathways: RTK Signaling