Ephrin B3 antibody (AA 28-226)

Catalog No. ABIN7151880

The Rabbit Polyclonal anti-Ephrin B3 antibody has been validated for WB, ELISA and IHC. It is suitable to detect Ephrin B3 in samples from Human.

Quick Overview for Ephrin B3 antibody (AA 28-226) (ABIN7151880)

Target: Ephrin B3 (EFNB3)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ephrin B3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-Ephrin B3 Antibody

Binding Specificity: AA 28-226

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Ephrin-B3 protein (28-226AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Ephrin B3

Target: Ephrin B3 (EFNB3)

Alternative Name: EFNB3

Background:

Background: Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. May play a pivotal role in forebrain function. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons (By similarity).

Aliases: EFL 6 antibody, EFL6 antibody, EFNB 3 antibody, Efnb3 antibody, EFNB3_HUMAN antibody, EPH related receptor transmembrane ligand ELK L3 antibody, EPH related receptor transmembrane ligand ELKL3 antibody, EPH related receptor tyrosine kinase ligand 8 antibody, EPH-related receptor transmembrane ligand ELK-L3 antibody, EPH-related receptor tyrosine kinase ligand 8 antibody, Ephrin B3 antibody, Ephrin-B3 antibody, EphrinB3 antibody, EPLG 8 antibody, EPLG8 antibody, LERK 8 antibody, LERK-8 antibody, LERK8 antibody

UniProt: Q15768

Pathways: RTK Signaling