EIF3C antibody (AA 201-500)

Catalog No. ABIN7152149

This Rabbit Polyclonal antibody specifically detects EIF3C in WB, ELISA, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for EIF3C antibody (AA 201-500) (ABIN7152149)

Target: EIF3C (Eukaryotic Translation Initiation Factor 3 Subunit C (EIF3C))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF3C antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-EIF3C Antibody

Binding Specificity: AA 201-500

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Eukaryotic translation initiation factor 3 subunit C protein (201-500AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:2000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for EIF3C

Target: EIF3C (Eukaryotic Translation Initiation Factor 3 Subunit C (EIF3C))

Alternative Name: EIF3C

Background:

Background: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

Aliases: Cell migration inducing protein 17 antibody, eIF 3c antibody, eIF3 p110 antibody, eIF3-p110 antibody, eIF3c antibody, EIF3C_HUMAN antibody, EIF3CL antibody, EIF3S8 antibody, EIF3S8 protein antibody, Eukaryotic translation initiation factor 3 subunit 8 (110kD) antibody, Eukaryotic translation initiation factor 3 subunit 8 110 kDa antibody, Eukaryotic translation initiation factor 3 subunit 8 antibody, Eukaryotic translation initiation factor 3 subunit C antibody

UniProt: Q99613

Pathways: Ribonucleoprotein Complex Subunit Organization