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EIF3C antibody (N-Term)
EIF3C
Reactivity: Human
WB, EIA, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-EIF3C Antibody
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Target
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EIF3C
(Eukaryotic Translation Initiation Factor 3 Subunit C (EIF3C))
Binding Specificity
All epitopes for EIF3C antibodies
AA 126-155, N-Term
Reactivity
All reactivities for EIF3C antibodies
Human
Host
All hosts for EIF3C antibodies
Rabbit
Clonality
All clonalities for EIF3C antibodies
Polyclonal
Conjugate
All conjugates for EIF3C antibodies
This EIF3C antibody is un-conjugated
Application
All applications for EIF3C antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificity
This antibody recognizes EIF3CL (N-term).
Cross-Reactivity (Details)
Species reactivity (expected):Bovine, Mouse, Rat. Species reactivity (tested):Human.
Purification
Affinity chromatography on Protein A
Immunogen
KLH conjugated synthetic peptide between 126-155 amino acids from the N-terminal region of human EIF3CL
Isotype
Ig Fraction
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS, 0.09 % (W/V) Sodium Azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for EIF3C
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Target
EIF3C
(Eukaryotic Translation Initiation Factor 3 Subunit C (EIF3C))
Alternative Name
EIF3C / EIF3S8 (EIF3C Products )
Synonyms
eif3s8 antibody, fi37c04 antibody, zgc:66128 antibody, wu:fb34a08 antibody, wu:fi37c04 antibody, EIF3S8 antibody, EIF3CL antibody, eif3-p110 antibody, LOC733086 antibody, eIF3c antibody, eIF3-S8 antibody, AO090011000340 antibody, eIF3-p110 antibody, 110kDa antibody, 3230401O13Rik antibody, Eif3s8 antibody, NIPIL(A3) antibody, NipilA3 antibody, Xs antibody, Xsl antibody, EIF3C antibody, eukaryotic translation initiation factor 3, subunit C antibody, eukaryotic translation initiation factor 3 subunit C antibody, eukaryotic translation initiation factor 3 subunit 8 antibody, Eukaryotic translation initiation factor 3 subunit C antibody, translation initiation factor eIF3c antibody, translation initiation factor eIF-3 subunit 8 antibody, eukaryotic translation initiation factor 3 subunit C L homeolog antibody, eukaryotic translation initiation factor 3, subunit C-like antibody, eif3c antibody, LOC454016 antibody, LOC479795 antibody, EIF3C antibody, Smp_000480 antibody, eIF3c antibody, ANI_1_1094124 antibody, AOR_1_578054 antibody, PTRG_08272 antibody, SJAG_04981 antibody, TERG_03202 antibody, PGTG_09255 antibody, Tsp_05110 antibody, Eif3c antibody, eif3c.L antibody, EIF3CL antibody, eif-3.C antibody
Background
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.Synonyms: Eukaryotic translation initiation factor 3 subunit 8, Eukaryotic translation initiation factor 3 subunit C, eIF3 p110
Molecular Weight
105344 Da
Gene ID
8663
NCBI Accession
NP_001032897
Pathways
Ribonucleoprotein Complex Subunit Organization
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