EIF3H antibody (AA 80-340)
Quick Overview for EIF3H antibody (AA 80-340) (ABIN7152160)
Target
See all EIF3H AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 80-340
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Cross-Reactivity
- Human, Rat
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Purification
- Antigen Affinity Purified
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Immunogen
- Recombinant Human Eukaryotic translation initiation factor 3 subunit H protein (80-340AA)
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Isotype
- IgG
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Application Notes
- Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- EIF3H (Eukaryotic Translation Initiation Factor 3 Subunit H (EIF3H))
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Alternative Name
- EIF3H
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Background
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Background: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
Aliases: eIF-3-gamma antibody, eIF3 gamma antibody, eIF3 p40 antibody, eIF3 p40 subunit antibody, eIF3h antibody, EIF3H_HUMAN antibody, EIF3S3 antibody, Eukaryotic translation initiation factor 3 subunit 3 antibody, Eukaryotic translation initiation factor 3 subunit H antibody, MGC102958 antibody
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UniProt
- O15372
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Pathways
- Ribonucleoprotein Complex Subunit Organization
Target
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