FBXO22 antibody (AA 104-403)

Catalog No. ABIN7152411

Product Details anti-FBXO22 Antibody

Target: FBXO22 (F-Box Protein 22 (FBXO22))

Binding Specificity: AA 104-403

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO22 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human F-box only protein 22 protein (104-403AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for FBXO22

Target: FBXO22 (F-Box Protein 22 (FBXO22))

Alternative Name: FBXO22 (FBXO22 Products)

Synonyms: FBXO22 antibody, DKFZp469L0535 antibody, fbxo22 antibody, MGC146708 antibody, si:busm1-132m23.3 antibody, FBX22 antibody, FISTC1 antibody, 0610033L19Rik antibody, 1600016C16Rik antibody, F-box protein 22 antibody, FBXO22 antibody, fbxo22 antibody, Fbxo22 antibody

Background:

Background: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Promotes the proteasome-dependent degradation of key sarcomeric proteins, such as alpha-actinin (ACTN2) and filamin-C (FLNC), essential for maintenance of normal contractile function.

Aliases: 0610033L19Rik antibody, 1600016C16Rik antibody, F box only protein 22 antibody, F box protein 22 antibody, F box protein FBX22p44 antibody, F-box only protein 22 antibody, F-box protein FBX22p44 antibody, FBX22 antibody, FBX22_HUMAN antibody, FBXO 22 antibody, FBXO22 antibody, FIST domain containing 1 antibody, FISTC1 antibody, FLJ13986 antibody, MGC124731 antibody, MGC31799 antibody

UniProt: Q8NEZ5

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development