FBXO7 antibody (AA 353-522)

Catalog No. ABIN7152449

This Rabbit Polyclonal antibody specifically detects FBXO7 in ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for FBXO7 antibody (AA 353-522) (ABIN7152449)

Target: FBXO7 (F-Box Protein 7 (FBXO7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO7 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-FBXO7 Antibody

Binding Specificity: AA 353-522

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human F-box only protein 7 protein (353-522AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for FBXO7

Target: FBXO7 (F-Box Protein 7 (FBXO7))

Alternative Name: FBXO7

Background:

Background: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes BIRC2 and DLGAP5. Plays a role downstream of PINK1 in the clearance of damaged mitochondria via selective autophagy (mitophagy) by targeting PARK2 to dysfunctional depolarized mitochondria. Promotes MFN1 ubiquitination.

Aliases: F box only protein 7 antibody, F box protein 7 antibody, F-box only protein 7 antibody, FBX antibody, FBX07 antibody, FBX7 antibody, FBX7_HUMAN antibody, Fbxo7 antibody, PARK15 antibody, PKPS antibody

UniProt: Q9Y3I1