Fibrinogen beta Chain antibody (AA 346-465) (Biotin)

Catalog No. ABIN7152760

This anti-Fibrinogen beta Chain antibody is a Rabbit Polyclonal antibody detecting Fibrinogen beta Chain in ELISA. Suitable for Human.

Quick Overview for Fibrinogen beta Chain antibody (AA 346-465) (Biotin) (ABIN7152760)

Target: Fibrinogen beta Chain (FGB)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fibrinogen beta Chain antibody is conjugated to Biotin

Application: ELISA

Product Details anti-Fibrinogen beta Chain Antibody (Biotin)

Binding Specificity: AA 346-465

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Fibrinogen beta chain protein (346-465AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Fibrinogen beta Chain

Target: Fibrinogen beta Chain (FGB)

Alternative Name: FGB

Background:

Background: Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.

Aliases: Beta fibrinogen antibody, Epididymis Secretory Sperm Binding Protein Li 78p antibody, FGB antibody, FIBB_HUMAN antibody, Fibrinogen beta chain antibody, Fibrinogen, B Beta Polypeptide antibody, HEL-S-78p antibody

UniProt: P02675