FZD9 antibody (AA 23-229) (HRP)

Catalog No. ABIN7153200

The Rabbit Polyclonal anti-FZD9 antibody has been validated for ELISA. It is suitable to detect FZD9 in samples from Human.

Quick Overview for FZD9 antibody (AA 23-229) (HRP) (ABIN7153200)

Target: FZD9 (Frizzled Family Receptor 9 (FZD9))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FZD9 antibody is conjugated to HRP

Application: ELISA

Product Details anti-FZD9 Antibody (HRP)

Binding Specificity: AA 23-229

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Frizzled-9 protein (23-229AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for FZD9

Target: FZD9 (Frizzled Family Receptor 9 (FZD9))

Alternative Name: FZD9

Background:

Background: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.

Aliases: CD 349 antibody, CD 349 antigen antibody, CD349 antibody, Frizzled Drosophila homolog of 3 antibody, Frizzled homolog 9 (Drosophila) antibody, Frizzled homolog 9 antibody, Frizzled-9 antibody, Fz 9 antibody, Fz-9 antibody, FZD 3 antibody, Fzd 9 antibody, FZD3 antibody, FZD3-PEN antibody, FZD9 antibody, FZD9_HUMAN antibody, FzE6 antibody, hFz9 antibody, mfz9 antibody, Xfz9 antibody

UniProt: O00144

Pathways: WNT Signaling