FBP1 antibody (AA 1-338)

Catalog No. ABIN7153202

This Rabbit Polyclonal antibody specifically detects FBP1 in ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for FBP1 antibody (AA 1-338) (ABIN7153202)

Target: FBP1 (Fructose-1,6-Bisphosphatase 1 (FBP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBP1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-FBP1 Antibody

Binding Specificity: AA 1-338

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Fructose-1,6-bisphosphatase 1 protein (1-338AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for FBP1

Target: FBP1 (Fructose-1,6-Bisphosphatase 1 (FBP1))

Alternative Name: FBP1

Background:

Background: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity, increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain.

Aliases: 6-bisphosphatase 1 antibody, 6-bisphosphate 1-phosphohydrolase 1 antibody, D fructose 1 6 bisphosphate 1 phosphohydrolase 1 antibody, D-fructose-1 antibody, EC 3.1.3.11 antibody, F16P1_HUMAN antibody, FBP antibody, FBP 1 antibody, FBP1 antibody, FBPase 1 antibody, Fructose 1 6 bisphosphatase 1 antibody, Fructose bisphosphatase 1 antibody, Fructose-1 antibody, Growth inhibiting protein 17 antibody, Liver fructose bisphosphatase antibody

UniProt: P09467

Pathways: Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Dicarboxylic Acid Transport