GPR143 antibody (AA 314-404) (HRP)

Catalog No. ABIN7153326

The Rabbit Polyclonal anti-GPR143 antibody has been validated for ELISA. It is suitable to detect GPR143 in samples from Human.

Quick Overview for GPR143 antibody (AA 314-404) (HRP) (ABIN7153326)

Target: GPR143 (G Protein-Coupled Receptor 143 (GPR143))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR143 antibody is conjugated to HRP

Application: ELISA

Product Details anti-GPR143 Antibody (HRP)

Binding Specificity: AA 314-404

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human G-protein coupled receptor 143 protein (314-404AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for GPR143

Target: GPR143 (G Protein-Coupled Receptor 143 (GPR143))

Alternative Name: GPR143

Background:

Background: Receptor for tyrosine, L-DOPA and dopamine. After binding to L-DOPA, stimulates Ca(2+) influx into the cytoplasm, increases secretion of the neurotrophic factor SERPINF1 and relocalizes beta arrestin at the plasma membrane, this ligand-dependent signaling occurs through a G(q)-mediated pathway in melanocytic cells. Its activity is mediated by G proteins which activate the phosphoinositide signaling pathway. Plays also a role as an intracellular G protein-coupled receptor involved in melanosome biogenesis, organization and transport.

Aliases: ALBINISM OCULAR TYPE I antibody, G protein coupled receptor 143 antibody, G-protein coupled receptor 143 antibody, GP143_HUMAN antibody, GPR143 antibody, MOA1 antibody, NETTLESHIP FALLS TYPE OCULAR ALBINISM antibody, Ocular albinism type 1 protein antibody, Ocular albinism type 1 protein homolog antibody, Ocular albinism1 Nettleship Falls type antibody

UniProt: P51810