GPR143 antibody (AA 120-200)

Catalog No. ABIN7222854

The Rabbit Polyclonal anti-GPR143 antibody (ABIN7222854) specifically detects GPR143 in ELISA and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for GPR143 antibody (AA 120-200) (ABIN7222854)

Target: GPR143 (G Protein-Coupled Receptor 143 (GPR143))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR143 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Product Details anti-GPR143 Antibody

Binding Specificity: AA 120-200

Purpose: Rabbit Anti-GPR143 Polyclonal Antibody

Specificity: GPR143 Polyclonal Antibody detects endogenous levels of GPR143 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human GPR143 at AA range: 120-200

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF 1:200-1:1000,ELISA 1:10000,Not yet tested in other applications,

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GPR143

Target: GPR143 (G Protein-Coupled Receptor 143 (GPR143))

Alternative Name: GPR143

Background: GPR143, OA1, G-protein coupled receptor 143, Ocular albinism type 1 proteinGPR143 encodes a protein that binds to heterotrimeric G proteins and is targeted to melanosomes in pigment cells. This protein is thought to be involved in intracellular signal transduction mechanisms. Mutations in GPR143 cause ocular albinism type 1, also referred to as Nettleship-Falls type ocular albinism, a severe visual disorder. A related pseudogene has been identified on chromosome Y.

Gene ID: 4935

UniProt: P51810