GPSM1 antibody (AA 60-300) (Biotin)
Quick Overview for GPSM1 antibody (AA 60-300) (Biotin) (ABIN7153372)
Target
See all GPSM1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 60-300
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Cross-Reactivity
- Human
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Purification
- >95%, Protein G purified
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Immunogen
- Recombinant Human G-protein-signaling modulator 1 protein (60-300AA)
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- GPSM1 (G-Protein Signaling Modulator 1 (GPSM1))
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Alternative Name
- GPSM1
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Background
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Background: Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G-protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein-coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction.
Aliases: Activator of G-protein signaling 3 antibody, AGS3 antibody, AGS3 homolog antibody, C10a antibody, G protein signaling modulator 1 (AGS3 like, C. elegans) antibody, G-protein-signaling modulator 1 antibody, GPSM1 antibody, GPSM1_HUMAN antibody
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UniProt
- Q86YR5
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Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling
Target
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