GPSM1 antibody (Internal Region)

Catalog No. ABIN7220958

The Rabbit Polyclonal anti-GPSM1 antibody is suitable to detect GPSM1 in samples from Human, Mouse and Rat. It has been validated for ELISA, IHC and IF.

Quick Overview for GPSM1 antibody (Internal Region) (ABIN7220958)

Target: GPSM1 (G-Protein Signaling Modulator 1 (GPSM1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPSM1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-GPSM1 Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-AGS3 Polyclonal Antibody

Specificity: AGS3 Polyclonal Antibody detects endogenous levels of AGS3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human AGS3

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GPSM1

Target: GPSM1 (G-Protein Signaling Modulator 1 (GPSM1))

Alternative Name: AGS3

Background: GPSM1, AGS3, G-protein-signaling modulator 1, Activator of G-protein signaling 3G-protein signaling modulators (GPSMs) play diverse functional roles through their interaction with G-protein subunits. GPSM1 encodes a receptor-independent activator of G protein signaling, which is one of several factors that influence the basal activity of G-protein signaling systems. The G-protein signaling modulator 1 contains seven tetratricopeptide repeats in its N-terminal half and four G-protein regulatory (GPR) motifs in its C-terminal half. Multiple alternatively spliced transcript variants encoding different isoforms have been found for GPSM1.

Gene ID: 26086

UniProt: Q86YR5

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling